Does My Mouse Already Exist?
CRISPR/Cas9 Injections: *NEW*
Generation of CRISPR-mediated insertions, deletions, point mutations, and gene replacements in mouse embryos
- SIGMA-partnered core to produce validated CRISPR RNAs
- Alliance with The Jackson Laboratory mouse model generation services
ES Cell Gene Targeting:
Partnered with Ingenious Targeting Laboratory for gene targeting projects in C57BL/6,129 SvEv, or hybrid ES cells
Blastocyst injections of ES cell clones and chimera breeding to germline transmission
Transgenic Mice Production:
Plasmid or BAC constructs injected on FVB, C57BL/6, or B6D2F1 backgrounds.
Embryo and Sperm Cryopreservation:
Cryopreserve your strain via embryo or sperm freezing with high QC standard, 30 year storage included in the fee.
Rederive any line with your frozen or live sperm, as well as frozen or live embryos
In Vitro Fertilizaton (IVF):
Importing a new line or expanding a low producing line
Timed Mating and Embryo Collection:
Natural or superovulated pregnancies, includes plug checking and embryo harvesting
in vivo validation of iPSCs. (flank, testes or kidney capsule)
If it involves mice or ES cells, give us a call. We are here to share our expertise with you.