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Sadan, O., Singbartl, K., Kraft, J. et al. Low-chloride- versus high-chloride-containing hypertonic solution for the treatment of subarachnoid hemorrhage–related complications: The ACETatE (A low ChloriE hyperTonic solution for brain Edema) randomized trial. j intensive care 8, 32 (2020).
Sanyal A, DeAndrade MP, Novis HS, Lin S, Chang J, Lengacher N, Tomlinson JJ, Tansey MG, LaVoie MJ. Lysosome and Inflammatory Defects in GBA1-Mutant Astrocytes Are Normalized by LRRK2 Inhibition. Mov Disord. 2020 May;35(5):760-773. doi: 10.1002/mds.27994. Epub 2020 Feb 8. PMID: 32034799; PMCID: PMC8167931.
Godfrey JR, Pincus M, Kovacs-Balint Z, Feczko E, Earl E, Miranda-Dominguez O, Fair DA, Jones SR, Locke J, Sanchez MM, Wilson ME, Michopoulos V. Obesogenic diet-associated C-reactive protein predicts reduced central dopamine and corticostriatal functional connectivity in female rhesus monkeys. Brain Behav Immun. 2020 Mar 30: S0889-1591(19)31625-3. doi: 10.1016/j.bbi.2020.03.030. PMID: 32240763.
Fonkoue IT, Marvar PJ, Norrholm S, Li Y, Kankam ML, Jones TN, Vemulapalli M, Rothbaum B, Bremner JD, Le NA, Park J. Symptom severity impacts sympathetic dysregulation and inflammation in post-traumatic stress disorder (PTSD). Brain Behav Immun. 2020 Jan;83:260-269. doi: 10.1016/j.bbi.2019.10.021. Epub 2019 Nov 1. PMID: 31682970; PMCID: PMC6906238.
De Sousa Rodrigues ME, Houser MC, Walker DI, Jones DP, Chang J, Barnum CJ, Tansey MG. Targeting soluble tumor necrosis factor as a potential intervention to lower risk for late-onset Alzheimer's disease associated with obesity, metabolic syndrome, and type 2 diabetes. Alzheimers Res Ther. 2019 Dec 31;12(1):1. doi: 10.1186/s13195-019-0546-4. PMID: 31892368; PMC6937979.
Eidson LN, deSousa Rodrigues ME, Johnson MA, Barnum CJ, Duke BJ, Yang Y, Chang J, Kelly SD, Wildner M, Tesi RJ, Tansey MG. Chronic psychological stress during adolescence induces sex-dependent adulthood inflammation, increased adiposity, and abnormal behaviors that are ameliorated by selective inhibition of soluble tumor necrosis factor with XPro1595. Brain Behav Immun. 2019 Oct;81:305-316. doi: 10.1016/j.bbi.2019.06.027. Epub 2019 Jun 25. PMID: 31251975; PMCID: PMC8597195.
Houser MC, Chang J, Factor SA, Molho ES, Zabetian CP, Hill-Burns EM, Payami H, Hertzberg VS, Tansey MG. Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease. Mov Disord. 2018 May;33(5):793-804. doi: 10.1002/mds.27326. Epub 2018 Mar 23. PMID: 29572994; PMCID: PMC5992021.
MacPherson KP, Sompol P, Kannarkat GT, Chang J, Sniffen L, Wildner ME, Norris CM, Tansey MG. Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice. Neurobiol Dis. 2017 Jun;102:81-95. doi: 10.1016/j.nbd.2017.02.010.
Lee, J-K, Kannarkat, GT; Chung, J, Lee ,H, Graham KL, Tansey M.G. (2016). RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis, Journal of Neuroinflammation, 2016 Feb 1;13(1):24. doi: 10.1186/s12974-016-0491-0.
Kannarkat, G., Cook, D.A., Lee, J-K., Chang, J., Chung, J., E. Sandy, E., Factor, S., Boss, J.M. , and Tansey M.G. (2015) Common genetic variant association with altered HLA expression, synergy with pyrethroid exposure, and risk for Parkinson’s disease: an observational and case–control study. Nature Partner Journal Parkinson’s Disease – 1, Article number: 15002 (2015) doi:10.1038/npjparkd.2015.2
Kannarkat, G.T., Ramsey, C.P., Chung, J., Chang, J., Porter, I., Oliver, D., Shepherd, K., Lee, J-K., and Tansey, M.G., (2015) Age-related changes in Regulator of G-protein Signaling (RGS)-10 expression in peripheral and central immune cells may influence risk for age-related degeneration, Neurobiology of Aging, 2015 May;36(5):1982-93. doi: 10.1016/j.neurobiolaging.2015.02.006. Epub 2015 Feb 13.
Chen, X., Chang, J., Deng, Q. Xu, J., Nguyen, T.A., Martens, L.H., Cenik, B., Taylor, G., Hudson, K.F., Chung, J., Yu, K., Yu, P., Herz, J., Farese Jr., R.V., Kukar, T., and Tansey M.G. (2013) Progranulin does not bind Tumor Necrosis Factor (TNF) Receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells, J Neuroscience 33(21): 9202-9213.
Lee, J-K., Chung, J., Kannarkat, G.T., and Tansey, M.G. (2013) Critical Role of Regulator G-protein Signaling 10 (RGS10) in Modulating Macrophage M1/M2 Activation, PLoS ONE, Nov 21;8(11):e81785. doi: 10.1371/journal.pone.0081785.
Harms, A.S., Lee, J-K., Ruhn, K.A., Treviño, I., and Tansey, M.G. (2012) Regulation of Microglia Effector Functions by Tumor Necrosis Factor (TNF) Signaling, Glia 60:189-202.
Lee, J-K., Chung, J., McAlpine, F.E., and Tansey, M.G. (2011) Regulator of G-protein Signaling-10 negatively regulates NF-kB in microglia and neuroprotects dopaminergic neurons in hemiparkinsonian rats, J Neurosci, (33):11879-88.
Tran, T.A., 1, Nguyen, A.D., Goldberg, M.S., and Tansey, M.G. (2011) Lipopolysaccharide and Tumor Necrosis Factor regulate Parkin expression via Nuclear Factor-Kappa B, PLoS ONE, 2011;6 (8):e23660. Epub 2011 Aug 17. PMCID: PMC3157435