EPIC Services

As the EPIC core facility evolves so will the services provided.

Below is a list of services which will be available.

Cell Services

Cell Isolation

• Bone Marrow mononuclear cells isolation

• Peripheral blood cell isolation

• Magnetically coupled antibody selection

Sterility testing

• Bacteria

• Mycoplasma

• Endotoxin

Cell Propagation/modification

• Adherent (small scale)

• Suspension (small scale)

• Clinical Expansion (scale up)

• Other

Cell Freezing and Storage

• Computer controlled step-down freezing

• LN2 Vapor Phase storage

• LN2 liquid storage

Cell Characterization

• Immunophenotyping

• Differentiation

• Potency

Research Investigational Material

• Culture Expanded human Mesenchymal stromal cells
• Frozen Mononuclear cells from Bone marrow aspiration
• Frozen Peripheral blood mononuclear cells
• Human compatible cell culture growth supplement(s)

Consultation Services

Non-clinical

• Efficacy studies

• Potency studies

• Toxicity studies

Clinical

• Trial design

• Safety studies

Chemistry, Manufacturing and Content

• Cell Substance evaluation

• Cell product

• Manufacturing and packaging

• Quality assurnce

Pre-IND package preparation

IRB and IND package preparation