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Scislowicz E, Ding D, Griggs AG, Harbuzariu A, Itzhaki I. Generation of three induced pluripotent stem cell lines from a long QT syndrome type 2 family harboring the pathogenic KCNH2 c.209A > G (p.His70Arg) variant. Stem Cell Res. 2025 Oct;88:103827. doi: 10.1016/j.scr.2025.103827. Epub 2025 Sep 3. PMID: 40939557.
Woolpert KM, Ahern TP, Baurley JW, Maliniak ML, Damkier P, Kjærsgaard A, Collin LJ, Hamilton-Dutoit S, Tramm T, Ejlertsen B, Sørensen HT, Lash TL, Cronin-Fenton DP. Genetic variants in tamoxifen metabolism and early treatment discontinuation among premenopausal breast cancer patients. Breast Cancer Res Treat. 2025 Jul;212(2):251-260. doi: 10.1007/s10549-025-07719-1. Epub 2025 May 14. PMID: 40369345; PMCID: PMC12134019.
Jarrell ZR, Lee CM, Lee HY, Kim KH, Lim G, Orr M, Kang SM, Chen Y, Jones DP, Go YM. Cadmium exposure following early-life respiratory syncytial virus infection promotes lung fibrosis through autophagy inhibition. Toxicol Sci. 2025 Jul 1;206(1):123-133. doi: 10.1093/toxsci/kfaf054. PMID: 40268749; PMCID: PMC12198674.
Alexander KL, Bennion KB, Liu D, Ford ML. CD154:CD11b blockade enhances CD8+ T cell differentiation during infection but not transplantation. JCI Insight. 2025 Jun 9;10(11):e184843. doi: 10.1172/jci.insight.184843. PMID: 40485581; PMCID: PMC12220971.
Vaidya P, Khorrami M, Bera K, Fu P, Delasos L, Gupta A, Barrera C, Pennell NA, Velcheti V, Madabhushi A. Computationally integrating radiology and pathology image features for predicting treatment benefit and outcome in lung cancer. NPJ Precis Oncol. 2025 Jun 4;9(1):161. doi: 10.1038/s41698-025-00939-0. PMID: 40467921; PMCID: PMC12137726.
Yang J, Chen F, Fu Z, Yang F, Saba NF, Teng Y. Blocking the TCA Cycle in Cancer Cells Potentiates CD36+ T-cell-Mediated Antitumor Immunity by Suppressing ER Stress-Associated THBS2 Signaling. Cancer Res. 2025 Jun 2;85(11):2014-2026. doi: 10.1158/0008-5472.CAN-24-3477. PMID: 40293258; PMCID: PMC12129664.
Monroe C, Muñiz JP, Leong T, Lewis RW, Castellino SM. Disparities in Clinical Trial Participation in Children and Adolescent Patients With a Hematologic Malignancy. Pediatr Blood Cancer. 2025 Jun;72(6):e31641. doi: 10.1002/pbc.31641. Epub 2025 Mar 7. PMID: 40055873; PMCID: PMC12018119.
Dhodapkar KM, Castellino S, Kapadia S, Azeem MI, Horvat A, Lawrence T, DeRyckere D, Dhodapkar MV. Immune-aging at diagnosis determines T-cell recovery in childhood leukemia survivors. NPJ Aging. 2025 May 23;11(1):39. doi: 10.1038/s41514-025-00233-0. PMID: 40410231; PMCID: PMC12102316.
Gamboa L, Zamat AH, Thiveaud CA, Lee HJ, Kulaksizoglu E, Zha Z, Campbell NS, Chan CS, Fábrega S, Oliver SA, Su FY, Phuengkham H, Vanover D, Peck HE, Sivakumar A, Dahotre SN, Harris AM, Santangelo PJ, Kwong GA. Sensitizing solid tumors to CAR-mediated cytotoxicity by lipid nanoparticle delivery of synthetic antigens. Nat Cancer. 2025 Jun;6(6):1073-1087. doi: 10.1038/s43018-025-00968-5. Epub 2025 May 16. PMID: 40379831; PMCID: PMC12305469.
Janopaul-Naylor J, Yadalam AK, Chan JSK, Dee EC, Sun YV, Cantu SM, Mandawat A, Patel SA. Modifiable Cardiovascular Risk Factors Amongst Men With and Without Prostate Cancer in a Large, Prospective Registry. Clin Genitourin Cancer. 2025 Jun;23(3):102340. doi: 10.1016/j.clgc.2025.102340. Epub 2025 Mar 28. PMID: 40252318; PMCID: PMC12084126.
Li Z, Dunlop AL, Sarnat JA, Hüls A, Eick SM, Gaskins A, Chang H, Russell A, Tan Y, Cheng H, Barr DB, Smith AK, Marsit C, Jones DP, Liang D. Unraveling the Molecular Links between Fine Particulate Matter Exposure and Early Birth Risks in African American Mothers: A Metabolomics Study in the Atlanta African American Maternal-Child Cohort. Environ Sci Technol. 2025 Jun 10;59(22):10905-10918. doi: 10.1021/acs.est.5c02071. Epub 2025 May 29. PMID: 40440123; PMCID: PMC12164266.
Yadalam AK, Liu C, Sun YV, Mandawat A, Quyyumi AA, Hayek SS. Proteomics-Based Soluble Urokinase Plasminogen Activator Receptor Levels and Long-Term Cardiovascular Outcomes in Survivors of Breast Cancer: A UK Biobank Study. J Am Heart Assoc. 2025 May 6;14(9):e039728. doi: 10.1161/JAHA.124.039728. Epub 2025 May 2. PMID: 40314383; PMCID: PMC12184272.
Mumme HL, Huang C, Ohlstrom D, Bakhtiari M, Raikar SS, DeRyckere D, Qayed M, Castellino SM, Wechsler DS, Porter CC, Graham DK, Bhasin SS, Bhasin M. Identification of leukemia-enriched signature through the development of a comprehensive pediatric single-cell atlas. Nat Commun. 2025 May 2;16(1):4114. doi: 10.1038/s41467-025-59362-5. PMID: 40316535; PMCID: PMC12048633.
Wiggins KJ, Williams ME, Hicks SL, Padilla-Quirarte HO, Akther J, Randall TD, Boss JM, Scharer CD. EZH2 coordinates memory B-cell programming and recall responses. J Immunol. 2025 May 1;214(5):947-957. doi: 10.1093/jimmun/vkaf004. PMID: 40073167; PMCID: PMC12123212.
Janto NV, Gleizes AR, Sun SJ, Ari G, Rao V, Gracz AD. Tritrichomonas muris sensitizes the intestinal epithelium to doxorubicin-induced apoptosis. Am J Physiol Gastrointest Liver Physiol. 2025 May 1;328(5):G594-G609. doi: 10.1152/ajpgi.00242.2024. Epub 2025 Apr 17. PMID: 40243204; PMCID: PMC12094299.
Zhang W, Roversi FM, Morris AB, Ortiz K, Zhou G, Hadley A, Zhang X, Silva JAF, Breeden CP, Zhanzak Z, Kissick HT, Larsen CP. Major histocompatibility complex and peptide specificity underpin CD8+ T cell direct alloresponse. Am J Transplant. 2025 May;25(5):916-929. doi: 10.1016/j.ajt.2024.10.011. Epub 2024 Oct 20. PMID: 39433089.
Chi JJ, Xie P, Cheng MH, Zhu Y, Cui X, Watson J, Zeng L, Uddin A, Nguyen H, Li L, Moremen K, Reedy A, Wyatt M, Marcus A, Dai M, Paulos CM, Cristofanilli M, Gradishar WJ, Zhao S, Kalinsky K, Hung MC, Bahar I, Zhang B, Wan Y. MGAT1-Guided complex N-Glycans on CD73 regulate immune evasion in triple-negative breast cancer. Nat Commun. 2025 Apr 15;16(1):3552. doi: 10.1038/s41467-025-58524-9. PMID: 40229283; PMCID: PMC11997035.
Morris AB, Adelman MW, Bennion KB, Martinez CD, McCook KM, Woodworth MH, Langelier CR, Rouphael N, Scharer CD, Maier CL, Kraft CS, Ford ML. Fgl2 regulates FcγRIIB+CD8+ T cell responses during infection. JCI Insight. 2025 Apr 8;10(7):e186259. doi: 10.1172/jci.insight.186259. PMID: 40197366; PMCID: PMC11981615.
Jin F, Gridley J, Kumari A, Saeidi A, Holland B, Elrod E, Dravid P, Trivedi S, Kapoor A, Thapa M, Grakoui A. Hyperfunctional T cell responses unchecked by regulatory T cells are unable to resolve hepaciviral infection without humoral contribution. J Hepatol. 2025 Apr;82(4):604-614. doi: 10.1016/j.jhep.2024.10.012. Epub 2024 Oct 17. PMID: 39423870; PMCID: PMC11911089.
Teeny S, Jarrell ZR, Krigbaum NY, Cirillo PM, Go YM, Cohn BA, Jones DP. Environmental basis for early onset breast cancer. Reprod Toxicol. 2025 Apr;133:108866. doi: 10.1016/j.reprotox.2025.108866. Epub 2025 Feb 25. PMID: 40015485; PMCID: PMC11996058.
Tilton M, Liao J, Kim C, Shaygani H, Potes MA, Cordova DJ, Kirkland JL, Miller KM. Tracing Cellular Senescence in Bone: Time-Dependent Changes in Osteocyte Cytoskeleton Mechanics and Morphology. Small. 2025 Apr;21(14):e2408517. doi: 10.1002/smll.202408517. Epub 2025 Mar 3. PMID: 40026102; Li J,
Zhan S, Yang W, Zhang H, Ma X, Chen F, Li A, Tong P, Jiang F, Cao Z, Delahunty I, Wang J, Wu Y, Liu Z, Li Z, Teng Y, Xu L, Xie J. Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol. J Nanobiotechnology. 2025 Mar 26;23(1):249. doi: 10.1186/s12951-025-03303-3. PMID: 40133959; PMCID: PMC11938788.PMCID: PMC11985287.
Bennion KB, Miranda R Bazzano J, Liu D, Wagener M, Paulos CM, Ford ML. Macrophage-derived Fgl2 dampens antitumor immunity through regulation of FcγRIIB+CD8+ T cells in melanoma. JCI Insight. 2025 Mar 24;10(6):e182563. doi: 10.1172/jci.insight.182563. PMID: 40125553; PMCID: PMC11949062.
Strickler HD, Usyk M, Eltoum IE, Bachman N, Hessol NA, Flowers L, Rahangdale L, Atrio JM, Ramirez C, Minkoff H, Adimora AA, Ofotokun I, Keller MJ, Fischl M, Shrestha S, Wright R, D'Souza G, Sanchez-Keeland L, Xie X, Xue X, Anastos K, Massad LS, Palefsky JM, Burk RD. Case-Control Study of Cervicovaginal β/γ-Human Papillomavirus Infection in Women With Human Immunodeficiency Virus and Its Relation to Incident Cervical Precancer. J Infect Dis. 2025 Mar 17;231(3):595-599. doi: 10.1093/infdis/jiae588. PMID: 39601267; PMCID: PMC11911781.
Cui X, Zhu Y, Zeng L, Zhang M, Uddin A, Gillespie TW, McCullough LE, Zhao S, Torres MA, Wan Y. Pharmacological Dissection Identifies Retatrutide Overcomes the Therapeutic Barrier of Obese TNBC Treatments through Suppressing the Interplay between Glycosylation and Ubiquitylation of YAP. Adv Sci (Weinh). 2025 Mar;12(11):e2407494. doi: 10.1002/advs.202407494. Epub 2025 Jan 27. PMID: 39868848; PMCID: PMC11923992.
Shu C, Li J, Rui J, Fan D, Niu Q, Bai R, Cicka D, Doyle S, Wahafu A, Zheng X, Du Y, Ivanov AA, Doxie DB, Dhodapkar KM, Carlisle J, Owonikoko T, Sica G, Liu Y, Ramalingam S, Dhodapkar MV, Zhou W, Mo X, Fu H. Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer. Nat Commun. 2025 Mar 8;16(1):2324. doi: 10.1038/s41467-025-57297-5. PMID: 40057483; PMCID: PMC11890758.
Kline EM, Jernigan JE, Scharer CD, Maurer J, Hicks Sl S, Herrick M MK, Wallings RL, Kelly SD, Chang J, Menees KB, McFarland NR, Boss JM, Tansey MG, Joers V. MHCII reduction is insufficient to protect mice from alpha-synuclein-induced degeneration and the Parkinson's HLA locus exhibits epigenetic regulation. bioRxiv [Preprint]. 2025 Mar 4:2024.08.31.610581. doi: 10.1101/2024.08.31.610581. Update in: Sci Rep. 2025 Apr 21;15(1):13705. doi: 10.1038/s41598-025-95679-3. PMID: 40093159; PMCID: PMC11908218.
Li Y, Thamizhchelvan AM, Ma H, Padelford J, Zhang Z, Wu T, Gu Q, Wang Z, Mao H. A subtype specific probe for targeted magnetic resonance imaging of M2 tumor-associated macrophages in brain tumors. Acta Biomater. 2025 Mar 1;194:336-351. doi: 10.1016/j.actbio.2025.01.003. Epub 2025 Jan 11. PMID: 39805525.
Kristoff TJ, Evans S, Nayi P, Abousaud M, Goyal S, Liu Y, Shin D, Steuer CE, Saba NF, Schmitt NC. Statin Drugs Are Associated With Response to Immune Checkpoint Blockade in Recurrent/Metastatic Head and Neck Cancer. Cancer Med. 2025 Mar;14(5):e70718. doi: 10.1002/cam4.70718. PMID: 40052634; PMCID: PMC11886884.
Case KB, Martini DJ, Dababneh MN, Bidot S, Nazha B, Brown J, Joshi S, Narayan V, Parihar V, Saeed F, Bilen MA, Harik LR. Trop-2 and Ephrin B2 expression in urothelial carcinoma with divergent differentiation and aggressive urothelial carcinoma subtypes. Am J Clin Pathol. 2025 Apr 19;163(4):618-628. doi: 10.1093/ajcp/aqae161. PMID: 39705501; PMCID: PMC12009667.
Khatib TO, Pedro BA, Bombin S, Matsuk VY, Robinson IE, Webster SF, Marcus LJ, Summerbell ER, Tharp GK, Knippler CM, Bagchi P, Kowalski-Muegge J, Johnston HR, Ghalei H, Vertino PM, Mouw JK, Marcus AI. TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion. Cell Rep. 2025 Feb 25;44(2):115315. doi: 10.1016/j.celrep.2025.115315. Epub 2025 Feb 15. PMID: 39955775; PMCID: PMC11951108.
Chen KY, De Giovanni M, Xu Y, An J, Kirthivasan N, Lu E, Jiang K, Brooks S, Ranucci S, Yang J, Kanameishi S, Kabashima K, Brulois K, Bscheider M, Butcher EC, Cyster JG. Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes. Cell. 2025 Feb 20;188(4):1019-1035.e22. doi: 10.1016/j.cell.2024.11.031. Epub 2024 Dec 20. PMID: 39708807; PMCID: PMC11845304.
Nair R, Vu AH, Freer AK, Bhatia KS, Wang D, Savani MR, Matulis SM, Lonial S, Jaye DL, Boise LH, Seo SY, Corson TW, Nooka AK, Bhatt S, McBrayer SK, Gupta VA, Hu X, Barwick BG, Reddi AR, Shanmugam M. Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis. Blood. 2025 Feb 13;145(7):732-747. doi: 10.1182/blood.2024025690. PMID: 39693611; PMCID: PMC12060166.
Zhanzak Z, Johnson AC, Foster P, Cardenas MA, Morris AB, Zhang J, Karadkhele G, Badell IR, Morris AA, Au-Yeung BB, Roversi FM, Silva JAF, Breeden C, Hadley A, Zhang W, Larsen CP, Kissick HT. Identification of indirect CD4+ T cell epitopes associated with transplant rejection provides a target for donor-specific tolerance induction. Immunity. 2025 Feb 11;58(2):448-464.e6. doi: 10.1016/j.immuni.2025.01.008. Epub 2025 Jan 30. PMID: 39889703.
Gibbs DC, McCrary MR, Moreno CS, Seldin L, Li C, Kamili NAH, Pollack BP. Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes. BMC Genomics. 2025 Feb 10;26(1):122. doi: 10.1186/s12864-025-11237-1. Erratum in: BMC Genomics. 2025 Mar 24;26(1):291. doi: 10.1186/s12864-025-11457-5. PMID: 39924511; PMCID: PMC11809098.
Farhi J, Emenike B, Lee RS, Sad K, Fawwal DV, Beusch CM, Jones RB, Verma AK, Jones CY, Foroozani M, Reeves M, Parwani KK, Bagchi P, Deal RB, Katz DJ, Corbett AH, Gordon DE, Raj M, Spangle JM. Dynamic In Vivo Mapping of the Methylproteome Using a Chemoenzymatic Approach. J Am Chem Soc. 2025 Mar 5;147(9):7214-7230. doi: 10.1021/jacs.4c08175. Epub 2025 Feb 25. PMID: 39996454; PMCID: PMC11887452.
Rong J, Zhao C, Chaudhary AF, Jones E, Van R, Song Z, Li Y, Chen J, Zhou X, Patel JS, Gao Y, Sun Z, Feng S, Zhang Z, Collier TL, Ran C, Haider A, Shao Y, Yuan H, Liang SH. Development of a Novel 18F-Labeled Radioligand for Imaging Phosphodiesterase 7 with Positron Emission Tomography. Mol Pharm. 2025 Mar 3;22(3):1657-1666. doi: 10.1021/acs.molpharmaceut.4c01379. Epub 2025 Feb 19. PMID: 39970438; PMCID: PMC11881136.
Janopaul-Naylor JR, Patel JS, Rupji M, Hoang KB, McCall NS, Qian DC, Shoaf ML, Kothari S, Olson JJ, Shu HG, Voloschin A, Zhong J, Neill SG, Eaton B. Impact of Systemic and Radiation Therapy on Survival of Primary Central Nervous System Lymphoma. Cancers (Basel). 2025 Feb 12;17(4):618. doi: 10.3390/cancers17040618. PMID: 40002213; PMCID: PMC11853249.
Li Y, Lim C, Dismuke T, Malawsky DS, Oasa S, Bruce ZC, Offenhäuser C, Baumgartner U, D'Souza RCJ, Edwards SL, French JD, Ock LSH, Nair S, Sivakumaran H, Harris L, Tikunov AP, Hwang D, Alicea Pauneto CDM, Maybury M, Hassall T, Wainwright B, Kesari S, Stein G, Piper M, Johns TG, Sokolsky-Papkov M, Terenius L, Vukojević V, McSwain LF, Gershon TR, Day BW. Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179. Nat Commun. 2025 Feb 4;16(1):1091. doi: 10.1038/s41467-024-54861-3. PMID: 39904981; PMCID: PMC11794477.
Sad K, Fawwal DV, Jones CY, Hill EJ, Skinner KT, Adams ML, Lustenberger S, Lee RS, Lohano SV, Elayavalli SR, Farhi J, Mehta CC, Lemon LD, Fasken MB, Hong AL, Sloan SA, Corbett AH, Spangle JM. Histone H3E50K remodels chromatin to confer oncogenic activity and support an EMT phenotype. NAR Cancer. 2025 Feb 3;7(1):zcaf002. doi: 10.1093/narcan/zcaf002. PMID: 39901931; PMCID: PMC11788928.
Sojka C, Wang HV, Bhatia TN, Li Y, Chopra P, Sing A, Voss A, King A, Wang F, Joseph K, Ravi VM, Olson J, Hoang K, Nduom E, Corces VG, Yao B, Sloan SA. Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma. Nat Cell Biol. 2025 Feb;27(2):347-359. doi: 10.1038/s41556-024-01583-9. Epub 2025 Jan 8. PMID: 39779941; PMCID: PMC12210326.
McGinnis HS, Corriher T, Janopaul-Naylor J, Goyal S, Liu Y, Wang Z, Patel SA. Utilization of Radical Prostatectomy Versus Radiation Therapy for Gleason Grade Group 5 Prostate Cancer Before and After USPSTF Grade D Recommendation Against Prostate-Specific Antigen Screening in 2012. Cancer Med. 2025 Feb;14(3):e70624. doi: 10.1002/cam4.70624. PMID: 39908168; PMCID: PMC11797301.
Zhang G, Pannucci A, Ivanov AA, Switchenko J, Sun SY, Sica GL, Liu Z, Huang Y, Schmitz JC, Owonikoko TK. Polo-like Kinase 1 Inhibitors Demonstrate In Vitro and In Vivo Efficacy in Preclinical Models of Small Cell Lung Cancer. Cancers (Basel). 2025 Jan 28;17(3):446. doi: 10.3390/cancers17030446. PMID: 39941812; PMCID: PMC11815996.
Pozzo E, Yedigaryan L, Giarratana N, Wang CC, Garrido GM, Degreef E, Marini V, Rinaldi G, van der Veer BK, Sassi G, Eelen G, Planque M, Fanzani A, Koh KP, Carmeliet P, Yustein JT, Fendt SM, Uyttebroeck A, Sampaolesi M. miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma. Cell Rep. 2025 Jan 28;44(1):115171. doi: 10.1016/j.celrep.2024.115171. Epub 2025 Jan 11. PMID: 39799567.
Xiao C, Peng G, Conneely KN, Zhao H, Felger JC, Wommack EC, Higgins KA, Shin DM, Saba NF, Bruner DW, Miller AH. DNA methylation profiles of cancer-related fatigue associated with markers of inflammation and immunometabolism. Mol Psychiatry. 2025 Jan;30(1):76-83. doi: 10.1038/s41380-024-02652-z. Epub 2024 Jul 9. PMID: 38977918.
Weinberg J, Liu KH, Lee CM, Crandall WJ, Cuevas AR, Druzak SA, Morgan ET, Jarrell ZR, Ortlund EA, Martin GS, Singer G, Strobel FH, Go YM, Jones DP. Mammalian hydroxylation of microbiome-derived obesogen, delta-valerobetaine, to homocarnitine, a 5-carbon carnitine analog. J Biol Chem. 2025 Jan;301(1):108074. doi: 10.1016/j.jbc.2024.108074. Epub 2024 Dec 13. PMID: 39675709; PMCID: PMC11773067.
Lin, F, Lin, S, Wang, J, Sellers, J, Chrenek, M, Nickerson, J, Boatright, J, Geisert, E. An improved method of transducing retinal canglion cells using AAV via transpupillary injection in adult mouse eyes. Molecular Vision. 2025 Jan 12; 31:1-9. http://www.molvis.org/molvis/v31/1.
Elkins C, Ye C, Sivasami P, Mulpur R, Diaz-Saldana PP, Peng A, Xu M, Chiang YP, Moll S, Rivera-Rodriguez DE, Cervantes-Barragan L, Wu T, Au-Yeung BB, Scharer CD, Ford ML, Kissick H, Li C. Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis. Sci Immunol. 2025 Jan 10;10(103):eadl4909. doi: 10.1126/sciimmunol.adl4909. Epub 2025 Jan 10. PMID: 39792637; PMCID: PMC11786953.
Schmidt JA, Hjorth CF, Farkas DK, Damkier P, Feddersen S, Hamilton-Dutoit S, Ejlertsen B, Lash TL, Ahern TP, Cronin-Fenton D. Genetic variants and social benefit receipt in premenopausal women with breast cancer treated with docetaxel: a Danish population-based cohort study. Breast Cancer Res Treat. 2025 Jan;209(1):73-84. doi: 10.1007/s10549-024-07474-9. Epub 2024 Sep 20. PMID: 39302578; PMCID: PMC11785639.
Zhan S, Cao Z, Li J, Chen F, Lai X, Yang W, Teng Y, Li Z, Zhang W, Xie J. Iron Oxide Nanoparticles Induce Macrophage Secretion of ATP and HMGB1 to Enhance Irradiation-Led Immunogenic Cell Death. Bioconjug Chem. 2025 Jan 15;36(1):80-91. doi: 10.1021/acs.bioconjchem.4c00488. Epub 2024 Dec 16. PMID: 39680043; PMCID: PMC11740999.
Liang D, Tang Z, Diver WR, Sarnat JA, Chow SS, Cheng H, Deubler EL, Tan Y, Eick SM, Jerrett M, Turner MC, Wang Y. Metabolomics Signatures of Exposure to Ambient Air Pollution: A Large-Scale Metabolome-Wide Association Study in the Cancer Prevention Study-II Nutrition Cohort. Environ Sci Technol. 2025 Jan 14;59(1):212-223. doi: 10.1021/acs.est.4c09592. Epub 2024 Dec 16. PMID: 39680091; PMCID: PMC11741098.
Chen F, Lang L, Yang J, Yang F, Tang S, Fu Z, Saba NF, Luo M, Teng Y. SMAC-armed oncolytic virotherapy enhances the anticancer activity of PD1 blockade by modulating PANoptosis. Biomark Res. 2025 Jan 9;13(1):8. doi: 10.1186/s40364-025-00726-w. PMID: 39789615; PMCID: PMC11721257.
Janardan SK, Lewis RW, Marchak JG, Mertens AC, Effinger KE. The association of perceived health status and presence of chronic conditions with physical activity in childhood cancer survivors. Support Care Cancer. 2025 Jan 15;33(2):98. doi: 10.1007/s00520-025-09157-7. PMID: 39810051; PMCID: PMC11887939.
Hicks SL, Scharer CD. Measuring B Cell Chromatin Accessibility by One-Step ATAC-seq. Methods Mol Biol. 2024;2826:55-63. doi: 10.1007/978-1-0716-3950-4_5. PMID: 39017885; PMCID: PMC11789530.
Akdogan-Ozdilek B, George-Alexander LMM, Scharer CD. Epigenomic Profiling of B Cell Subsets by CUT&Tag. Methods Mol Biol. 2024;2826:65-77. doi: 10.1007/978-1-0716-3950-4_6. PMID: 39017886; PMCID: PMC11753148.
Katrinli S, Wani AH, Maihofer AX, Ratanatharathorn A, Daskalakis NP, Montalvo-Ortiz J, Núñez-Ríos DL, Zannas AS, Zhao X, Aiello AE, Ashley-Koch AE, Avetyan D, Baker DG, Beckham JC, Boks MP, Brick LA, Bromet E, Champagne FA, Chen CY, Dalvie S, Dennis MF, Fatumo S, Fortier C, Galea S, Garrett ME, Geuze E, Grant G, Hauser MA, Hayes JP, Hemmings SMJ, Huber BR, Jajoo A, Jansen S, Kessler RC, Kimbrel NA, King AP, Kleinman JE, Koen N, Koenen KC, Kuan PF, Liberzon I, Linnstaedt SD, Lori A, Luft BJ, Luykx JJ, Marx CE, McLean SA, Mehta D, Milberg W, Miller MW, Mufford MS, Musanabaganwa C, Mutabaruka J, Mutesa L, Nemeroff CB, Nugent NR, Orcutt HK, Qin XJ, Rauch SAM, Ressler KJ, Risbrough VB, Rutembesa E, Rutten BPF, Seedat S, Stein DJ, Stein MB, Toikumo S, Ursano RJ, Uwineza A, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Young RM, Zhao Y, van den Heuvel LL; PGC-PTSD Epigenetics Workgroup; PsychENCODE PTSD Brainomics Project; Traumatic Stress Brain Research Group; Uddin M, Nievergelt CM, Smith AK, Logue MW. Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts. Genome Med. 2024 Dec 18;16(1):147. doi: 10.1186/s13073-024-01417-1. PMID: 39696436; PMCID: PMC11658418.
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Joyner CJ, Ley AM, Nguyen DC, Ali M, Corrado A, Tipton C, Scharer CD, Mi T, Woodruff MC, Hom J, Boss JM, Duan M, Gibson G, Roberts D, Andrews J, Lonial S, Sanz I, Lee FE. Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting. Life Sci Alliance. 2021 Dec 24;5(3):e202101285. doi: 10.26508/lsa.202101285. PMID: 34952892; PMCID: PMC8739272.
Lee M, Hamilton JAG, Talekar GR, Ross AJ, Michael L, Rupji M, Dwivedi B, Raikar SS, Boss J, Scharer CD, Graham DK, DeRyckere D, Porter CC, Henry CJ. Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia. Nat Commun. 2022 Mar 3;13(1):1157. doi: 10.1038/s41467-022-28839-y. PMID: 35241678; PMCID: PMC8894417.
Zhang H, Dammer EB, Duong DM, Danelia D, Seyfried NT, Yu DS. Quantitative proteomic analysis of the lysine acetylome reveals diverse SIRT2 substrates. Sci Rep. 2022 Mar 9;12(1):3822. doi: 10.1038/s41598-022-06793-5. PMID: 35264593; PMCID: PMC8907344.
Gohar J, Do WL, Miller-Kleinhenz J, Conneely K, Krishnamurti U, D'Angelo O, Gogineni K, Torres M, Gabram-Mendola S, McCullough LE. Neighborhood characteristics and breast tumor methylation: using epigenomics to explore cancer outcome disparities. Breast Cancer Res Treat. 2022 Feb;191(3):653-663. doi: 10.1007/s10549-021-06430-1. Epub 2022 Jan 3. PMID: 34978015.
Di Pietro A, Polmear J, Cooper L, Damelang T, Hussain T, Hailes L, O'Donnell K, Udupa V, Mi T, Preston S, Shtewe A, Hershberg U, Turner SJ, La Gruta NL, Chung AW, Tarlinton DM, Scharer CD, Good-Jacobson KL. Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection. Nat Immunol. 2022 Jan;23(1):86-98. doi: 10.1038/s41590-021-01077-y. Epub 2021 Nov 29. PMID: 34845392.
Funk CR, Wang S, Chen KZ, Waller A, Sharma A, Edgar CL, Gupta VA, Chandrakasan S, Zoine JT, Fedanov A, Raikar SS, Koff JL, Flowers CR, Coma S, Pachter JA, Ravindranathan S, Spencer HT, Shanmugam M, Waller EK. PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity. Blood. 2022 Jan 27;139(4):523-537. doi: 10.1182/blood.2021011597. Erratum in: Blood. 2022 Sep 22;140(12):1449-1451. PMID: 35084470; PMCID: PMC8796652.
Kania AK, Guo M, Scharer CD, Boss JM. Inhibition of H3K27me3 Demethylases Promotes Plasmablast Formation. Immunohorizons. 2021 Dec 8;5(12):918-930. doi: 10.4049/immunohorizons.2000087. PMID: 34880105; PMCID: PMC10197425.
Patterson DG, Kania AK, Price MJ, Rose JR, Scharer CD, Boss JM. An IRF4-MYC-mTORC1 Integrated Pathway Controls Cell Growth and the Proliferative Capacity of Activated B Cells during B Cell Differentiation In Vivo. J Immunol. 2021 Oct 1;207(7):1798-1811. doi: 10.4049/jimmunol.2100440. Epub 2021 Sep 1. PMID: 34470852; PMCID: PMC8455452.
Corrado A, Ramonell RP, Woodruff MC, Tipton C, Wise S, Levy J, DelGaudio J, Kuruvilla ME, Magliocca KR, Tomar D, Garimalla S, Scharer CD, Boss JM, Wu H, Gumber S, Fucile C, Gibson G, Rosenberg A, Sanz I, Lee FE. Extrafollicular IgD+ B cells generate IgE antibody secreting cells in the nasal mucosa. Mucosal Immunol. 2021 Sep;14(5):1144-1159. doi: 10.1038/s41385-021-00410-w. Epub 2021 May 28. PMID: 34050324; PMCID: PMC8160425.
Kang Y, Zhou Y, Li Y, Han Y, Xu J, Niu W, Li Z, Liu S, Feng H, Huang W, Duan R, Xu T, Raj N, Zhang F, Dou J, Xu C, Wu H, Bassell GJ, Warren ST, Allen EG, Jin P, Wen Z. A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies. Nat Neurosci. 2021 Aug 19. doi: 10.1038/s41593-021-00913-6. Epub ahead of print. PMID: 34413513.
Hiwa R, Nielsen HV, Mueller JL, Mandla R, Zikherman J. NR4A family members regulate T cell tolerance to preserve immune homeostasis and suppress autoimmunity. JCI Insight. 2021 Aug 3:151005. doi: 10.1172/jci.insight.151005. Epub ahead of print. PMID: 34343134.
Price MJ, Scharer CD, Kania AK, Randall TD, Boss JM. Conserved Epigenetic Programming and Enhanced Heme Metabolism Drive Memory B Cell Reactivation. J Immunol. 2021 Apr 1;206(7):1493-1504. doi: 10.4049/jimmunol.2000551. Epub 2021 Feb 24. PMID: 33627377; PMCID: PMC7988296.
Andueza A, Kumar S, Kim J, Kang DW, Mumme HL, Perez JI, Villa-Roel N, Jo H. Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study. Cell Rep. 2020 Dec 15;33(11):108491. doi: 10.1016/j.celrep.2020.108491. PMID: 33326796; PMCID: PMC7801938.
Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. J Biol Chem. 2021 Jan-Jun;296:100024. doi: 10.1074/jbc.RA120.016009. Epub 2020 Nov 22. PMID: 33410399; PMCID: PMC7949046.
Vigneswaran K, Boyd NH, Oh SY, Lallani S, Boucher A, Neill SG, Olson JJ, Read RD. YAP/TAZ Transcriptional Coactivators Create Therapeutic Vulnerability to Verteporfin in EGFR-mutant Glioblastoma. Clin Cancer Res. 2021 Mar 1;27(5):1553-1569. doi: 10.1158/1078-0432.CCR-20-0018. Epub 2020 Nov 10. PMID: 33172899.
Scharer CD, Fortner KA, Dragon JA, Tighe S, Boss JM, Budd RC. Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone lpr Mice. Immunohorizons. 2020 Oct 23;4(10):679-687. doi: 10.4049/immunohorizons.2000078. PMID: 33097564; PMCID: PMC8141279.
Babiker A, Bradley HL, Stittleburg VD, Ingersoll JM, Key A, Kraft CS, Waggoner JJ, Piantadosi A. Metagenomic sequencing to detect respiratory viruses in persons under investigation for COVID-19. J Clin Microbiol. 2020 Oct 16:JCM.02142-20. doi: 10.1128/JCM.02142-20. Epub ahead of print. PMID: 33067271.
Zhang Y, Ware MB, Zaidi MY, Ruggieri AN, Olson BM, Komar H, Farren MR, Nagaraju GP, Zhang C, Chen Z, Sarmiento JM, Ahmed R, Maithel SK, El-Rayes BF, Lesinski GB. Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer. Mol Cancer Ther. 2021 Jan;20(1):150-160. doi: 10.1158/1535-7163.MCT-19-0911. Epub 2020 Oct 9. PMID: 33037138; PMCID: PMC7790996..
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Scharer CD, Patterson DG, Mi T, Price MJ, Hicks SL, Boss JM. Antibody-secreting cell destiny emerges during the initial stages of B-cell activation. Nat Commun. 2020 Aug 10;11(1):3989. doi: 10.1038/s41467-020-17798-x. PMID: 32778653; PMCID: PMC7417592.
Inglis GAS, Zhou Y, Patterson DG, Scharer CD, Han Y, Boss JM, Wen Z, Escayg A. Transcriptomic and epigenomic dynamics associated with development of human iPSC-derived GABAergic interneurons. Hum Mol Genet. 2020 Aug 29;29(15):2579-2595. doi: 10.1093/hmg/ddaa150. PMID: 32794569; PMCID: PMC7471504.
Goldsmith DR, Bekhbat M, Le NA, Chen X, Woolwine BJ, Li Z, Haroon E, Felger JC. Protein and gene markers of metabolic dysfunction and inflammation together associate with functional connectivity in reward and motor circuits in depression. Brain Behav Immun. 2020 Aug;88:193-202. doi: 10.1016/j.bbi.2020.05.013. Epub 2020 May 5. PMID: 32387344; PMCID: PMC7415617.
Bekhbat M, Treadway MT, Goldsmith DR, Woolwine BJ, Haroon E, Miller AH, Felger JC. Gene signatures in peripheral blood immune cells related to insulin resistance and low tyrosine metabolism define a sub-type of depression with high CRP and anhedonia. Brain Behav Immun. 2020 Aug;88:161-165. doi: 10.1016/j.bbi.2020.03.015. Epub 2020 Mar 18. PMID: 32198016; PMCID: PMC7415632.
Obeng RC, Arnold RS, Ogan K, Master VA, Pattaras JG, Petros JA, Osunkoya AO. Molecular characteristics and markers of advanced clear cell renal cell carcinoma: Pitfalls due to intratumoral heterogeneity and identification of genetic alterations associated with metastasis. Int J Urol. 2020 Jul 8. doi: 10.1111/iju.14302. Epub ahead of print. PMID: 32638444.
Xiao C, Eldridge RC, Beitler JJ, Higgins KA, Chico CE, Felger JC, Wommack EC, Knobf T, Saba NF, Shin DM, Bruner DW, Miller AH. Association Among Glucocorticoid Receptor Sensitivity, Fatigue, and Inflammation in Patients With Head and Neck Cancer. Psychosom Med. 2020 Jun;82(5):508-516. doi: 10.1097/PSY.0000000000000816. PMID: 32515926; PMCID: PMC7905992..
Slavotinek A, Misceo D, Htun S, Mathisen L, Frengen E, Foreman M, Hurtig JE, Enyenihi L, Sterrett MC, Leung SW, Schneidman-Duhovny D, Estrada-Veras J, Duncan JL, Haaxma CA, Kamsteeg EJ, Xia V, Beleford D, Si Y, Douglas G, Treidene HE, van Hoof A, Fasken MB, Corbett AH. Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness. Hum Mol Genet. 2020 Aug 3;29(13):2218-2239. doi: 10.1093/hmg/ddaa108. PMID: 32504085; PMCID: PMC7399534..
Li Z, Sun C, Tao S, Osunkoya AO, Arnold RS, Petros JA, Zu X, Moreno CS. The JNK inhibitor AS602801 Synergizes with Enzalutamide to Kill Prostate Cancer Cells In Vitro and In Vivo and Inhibit Androgen Receptor Expression. Transl Oncol. 2020 Apr;13(4):100751. doi: 10.1016/j.tranon.2020.100751. Epub 2020 Mar 18. PMID: 32199273; PMCID: PMC7082632.
Collins CM, Scharer CD, Murphy TJ, Boss JM, Speck SH. Murine gammaherpesvirus infection is skewed toward Igλ+ B cells expressing a specific heavy chain V-segment. PLoS Pathog. 2020 Apr 30;16(4):e1008438. doi: 10.1371/journal.ppat.1008438. PMID: 32353066; PMCID: PMC7217478.
Grimsley-Myers CM, Isaacson RH, Cadwell CM, Campos J, Hernandes MS, Myers KR, Seo T, Giang W, Griendling KK, Kowalczyk AP. VE-cadherin endocytosis controls vascular integrity and patterning during development. J Cell Biol. 2020 May 4;219(5):e201909081. doi: 10.1083/jcb.201909081. PMID: 32232465; PMCID: PMC7199849.
Hayward SL, Scharer CD, Cartwright EK, Takamura S, Li ZT, Boss JM, Kohlmeier JE. Environmental cues regulate epigenetic reprogramming of airway-resident memory CD8+ T cells. Nat Immunol. 2020 Mar;21(3):309-320. doi: 10.1038/s41590-019-0584-x. Epub 2020 Jan 17. PMID: 31953534; PMCID: PMC7044042.
Majumder P, Lee JT, Rahmberg AR, Kumar G, Mi T, Scharer CD, Boss JM. A super enhancer controls expression and chromatin architecture within the MHC class II locus. J Exp Med. 2020 Feb 3;217(2):e20190668. doi: 10.1084/jem.20190668. PMID: 31753848; PMCID: PMC7041702.
Farren MR, Sayegh L, Ware MB, Chen HR, Gong J, Liang Y, Krasinskas A, Maithel SK, Zaidi M, Sarmiento JM, Kooby D, Patel P, El-Rayes B, Shaib W, Lesinski GB. Immunologic alterations in the pancreatic cancer microenvironment of patients treated with neoadjuvant chemotherapy and radiotherapy. JCI Insight. 2020 Jan 16;5(1):e130362. doi: 10.1172/jci.insight.130362. PMID: 31830001; PMCID: PMC7030821.
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Donaldson KJ, Wu WF, Skelton H, Markand S, Ferdous S, Sellers J, Chrenek MA, Gefke I, Kim SM, Rha J, Liao KL, Grossniklaus HE, Jiang Y, Kong J, Boatright JH, Nickerson JM. Analysis of Damage and Wound Healing in the Retinal Pigmented Epithelium. Adv Exp Med Biol. 2019;1185:425-430. doi: 10.1007/978-3-030-27378-1_70. PMID: 31884649; PMCID: PMC7362297.
Ferdous S, Grossniklaus HE, Boatright JH, Nickerson JM. Characterization of LSD1 Expression Within the Murine Eye. Invest Ophthalmol Vis Sci. 2019 Nov 1;60(14):4619-4631. doi: 10.1167/iovs.19-26728. PMID: 31675426; PMCID: PMC6827424.
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Haines RR, Scharer CD, Lobby JL, Boss JM. LSD1 Cooperates with Noncanonical NF-κB Signaling to Regulate Marginal Zone B Cell Development. J Immunol. 2019 Oct 1;203(7):1867-1881. doi: 10.4049/jimmunol.1900654. Epub 2019 Sep 6. PMID: 31492745; PMCID: PMC6761012.
Price MJ, Hicks SL, Bradley JE, Randall TD, Boss JM, Scharer CD. IgM, IgG, and IgA Influenza-Specific Plasma Cells Express Divergent Transcriptomes. J Immunol. 2019 Oct 15;203(8):2121-2129. doi: 10.4049/jimmunol.1900285. Epub 2019 Sep 9. PMID: 31501259; PMCID: PMC6783370.
Chandrasekaran S, Sasaki M, Scharer CD, Kissick HT, Patterson DG, Magliocca KR, Seykora JT, Sapkota B, Gutman DA, Cooper LA, Lesinski GB, Waller EK, Thomas SN, Kotenko SV, Boss JM, Moreno CS, Swerlick RA, Pollack BP. Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression. Mol Cancer Res. 2019 Dec;17(12):2395-2409. doi: 10.1158/1541-7786.MCR-19-0545. Epub 2019 Sep 23. PMID: 31548239; PMCID: PMC7339488.
Scharer CD, Blalock EL, Mi T, Barwick BG, Jenks SA, Deguchi T, Cashman KS, Neary BE, Patterson DG, Hicks SL, Khosroshahi A, Eun-Hyung Lee F, Wei C, Sanz I, Boss JM. Epigenetic programming underpins B cell dysfunction in human SLE. Nat Immunol. 2019 Aug;20(8):1071-1082. doi: 10.1038/s41590-019-0419-9. Epub 2019 Jul 1. PMID: 31263277; PMCID: PMC6642679.
Byun PK, Zhang C, Yao B, Wardwell-Ozgo J, Terry D, Jin P, Moberg K. The Taiman Transcriptional Coactivator Engages Toll Signals to Promote Apoptosis and Intertissue Invasion in Drosophila. Curr Biol. 2019 Sep 9;29(17):2790-2800.e4. doi: 10.1016/j.cub.2019.07.012. Epub 2019 Aug 8. PMID: 31402304; PMCID: PMC6736757.
Moran JD, Kim HH, Li Z, Moreno CS. SOX4 regulates invasion of bladder cancer cells via repression of WNT5a. Int J Oncol. 2019 Aug;55(2):359-370. doi: 10.3892/ijo.2019.4832. Epub 2019 Jun 26. PMID: 31268162; PMCID: PMC6615919.
Siegel BI, King TZ, Rupji M, Dwivedi B, Carter AB, Kowalski J, MacDonald TJ. Host Genome Variation is Associated with Neurocognitive Outcome in Survivors of Pediatric Medulloblastoma. Transl Oncol. 2019 Jul;12(7):908-916. doi: 10.1016/j.tranon.2019.03.004. Epub 2019 May 9. PMID: 31078964; PMCID: PMC6515414.
Zumaquero E, Stone SL, Scharer CD, Jenks SA, Nellore A, Mousseau B, Rosal-Vela A, Botta D, Bradley JE, Wojciechowski W, Ptacek T, Danila MI, Edberg JC, Bridges SL Jr, Kimberly RP, Chatham WW, Schoeb TR, Rosenberg AF, Boss JM, Sanz I, Lund FE. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation. Elife. 2019 May 15;8:e41641. doi: 10.7554/eLife.41641. PMID: 31090539; PMCID: PMC6544433.
Stone SL, Peel JN, Scharer CD, Risley CA, Chisolm DA, Schultz MD, Yu B, Ballesteros-Tato A, Wojciechowski W, Mousseau B, Misra RS, Hanidu A, Jiang H, Qi Z, Boss JM, Randall TD, Brodeur SR, Goldrath AW, Weinmann AS, Rosenberg AF, Lund FE. T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells. Immunity. 2019 May 21;50(5):1172-1187.e7. doi: 10.1016/j.immuni.2019.04.004. Epub 2019 May 7. PMID: 31076359; PMCID: PMC6929688.
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Haines RR, Barwick BG, Scharer CD, Majumder P, Randall TD, Boss JM. The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation. J Immunol. 2018 Nov 1;201(9):2799-2811. doi: 10.4049/jimmunol.1800952. Epub 2018 Sep 19. PMID: 30232138; PMCID: PMC6200601.
Sharma NV, Pellegrini KL, Ouellet V, Giuste FO, Ramalingam S, Watanabe K, Adam-Granger E, Fossouo L, You S, Freeman MR, Vertino P, Conneely K, Osunkoya AO, Trudel D, Mes-Masson AM, Petros JA, Saad F, Moreno CS. Identification of the Transcription Factor Relationships Associated with Androgen Deprivation Therapy Response and Metastatic Progression in Prostate Cancer. Cancers (Basel). 2018 Oct 11;10(10):379. doi: 10.3390/cancers10100379. PMID: 30314329; PMCID: PMC6210624.
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Swimm A, Giver CR, DeFilipp Z, Rangaraju S, Sharma A, Ulezko Antonova A, Sonowal R, Capaldo C, Powell D, Qayed M, Kalman D, Waller EK. Indoles derived from intestinal microbiota act via type I interferon signaling to limit graft-versus-host disease. Blood. 2018 Dec 6;132(23):2506-2519. doi: 10.1182/blood-2018-03-838193. Epub 2018 Sep 26. PMID: 30257880; PMCID: PMC6284212.
Kennedy EM, Powell DR, Li Z, Bell JSK, Barwick BG, Feng H, McCrary MR, Dwivedi B, Kowalski J, Dynan WS, Conneely KN, Vertino PM. Galactic Cosmic Radiation Induces Persistent Epigenome Alterations Relevant to Human Lung Cancer. Sci Rep. 2018 Apr 30;8(1):6709. doi: 10.1038/s41598-018-24755-8. PMID: 29712937; PMCID: PMC5928241.
Scharer CD, Barwick BG, Guo M, Bally APR, Boss JM. Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs. Nat Commun. 2018 Apr 27;9(1):1698. doi: 10.1038/s41467-018-04125-8. PMID: 29703886; PMCID: PMC5923265.
Guo M, Price MJ, Patterson DG, Barwick BG, Haines RR, Kania AK, Bradley JE, Randall TD, Boss JM, Scharer CD. EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production. J Immunol. 2018 Feb 1;200(3):1039-1052. doi: 10.4049/jimmunol.1701470. Epub 2017 Dec 29. PMID: 29288200; PMCID: PMC5780247.
Struebing FL, Wang J, Li Y, King R, Mistretta OC, English AW, Geisert EE. Differential Expression of Sox11 and Bdnf mRNA Isoforms in the Injured and Regenerating Nervous Systems. Front Mol Neurosci. 2017 Nov 2;10:354. doi: 10.3389/fnmol.2017.00354. PMID: 29209164; PMCID: PMC5701613.
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