Services
The Emory HPLC bioanalytical core offers the ability to identify and quantify monoamines, amino acids, purine bases, and nucleotides from a variety of biological samples. We also provide expertise to develop and validate HPLC methods.
Monoamine analyses using HPLC coupled to electrochemical detector. Analytes include dopamine, dihydroxyindolphenylacetic acid (DOPAC), homovanillic acid (HVA), norepinephrine, 3-methoxytramine (3-MT), 5-hydroxyindole-3-acetic acid (5-HIAA), 4-hydroxy-3-methoxyphenyl glycol (MHPG), serotonin (5-HT).
Bioactive purine analyses using HPLC coupled to photodiode array detector. Analytes include ATP, ADP, AMP, adenosine, adenine, GTP, GDP, GMP, guanosine, hypoxanthine, inosine, xanthine and uric acid.
Amino acid analyses using pre-column OPA derivatization HPLC coupled to electrochemical detector. Analytes include glutamate, glutamine, alanine, glycine, arginine, taurine, GABA, and tyrosine. Other essential amino acids analysis is upon requested.
We also offer custom analyses to develop and validate HPLC methods. Some examples such as;small molecule drugs, purines, pyrimidines and related molecules, electrochemically active compounds, neuromodulators, their precursors and metabolites.
| Service | Internal Rate | External Rate |
|---|---|---|
| Monoamine HPLC Analysis [1] | $ 33 | $ 52 |
| Purine HPLC Analysis [1] | $ 46 | $ 72 |
| Amino Acid HPLC Analysis [1,3] | $ 33 | $ 52 |
| Monoamine HPLC Analysis & Sample Preparation [2] | $ 71 | $ 111 |
| Amino Acid HPLC Analysis & Sample Preparation [2] | $ 71 | $ 111 |
| Purine HPLC Analysis & Sample Preparatiion [2] | $ 88 | $ 138 |
| Consulting [4] | $ 137 | $ 213 |
| Set-up [4] | $ 562 | $ 876 |
- HPLC Analysis: includes HPLC analysis, data analysis and report generation. Samples are prepared by the investigator.
- HPLC Analysis & Sample Preparation: includes sample preparation from tissues and cells and/or determination of sample protein concentration, HPLC analysis, data analysis and report generation. The prices are per sample basis.
- Amino acid analyses will incur a set-up fee to change HPLC columns and running conditions.
- Custom HPLC method development and validation will incur a set-up fee and consulting fee for the labor hours.