About
Mission & Vision
The Emory Integrated Metabolomics and Lipidomics Core (EIMLC) performs quantitative lipidomics and targeted metabolomics analyses on samples from a wide variety of biological matrices to support clinical and research efforts. These analyses provide enhanced understanding of lipid mediators and soluble metabolites whose abundance may be monitored as biomarkers to predict and follow the progression of a wide range of diseases, such as metabolic disorders (e.g. obesity, Type II diabetes, and NAFLD), neurodegenerative diseases (e.g. Alzheimer’s Disease and Parkinson’s Disease), and certain cancers (e.g. prostate and breast).
Core Leadership
Dr. Eric Ortlund, Ph.D
Professor & Scientific Director
Dr. Ortlund is a Professor of Biochemistry and Director of the Emory Integrated Metabolomics and Lipidomics Core (EIMLC). His lab focuses on using sophisticated structural biology techniques such as x-ray crystallography and mass spectrometry coupled with an array of biochemical techniques to gain a molecular level understanding of transcriptional signaling - with a particular focus on lipid mediated signaling and transport. His lab currently pursues structural and biochemical studies of human nuclear receptors, which are lipid regulated transcription factors that play central roles in development, metabolism, stress, and response to infection and vaccination. His group plays an active role in multiple collaborative research projects to examine the significance of lipid signaling pathways in infectious diseases such as tuberculosis.
Lab Website
Dr. Kristal Maner-Smith, Ph.D.
Core Director
kristal.m.maner-smith@emory.edu
Dr. Maner-Smith is the Core Director of the Emory Integrated Metabolomics and Lipidomics Core (EIMLC). She has over 15 years experience in lipidomics and is an expert in the development/validation of methods to quantify low abundance lipid classes and signaling lipids. Her research interests involve the application of lipidomics to better understand biological processes including obesity, metabolic disease, Alzheimer’s disease, and other inflammatory conditions. Using the Core’s existing infrastructure, she is excited to help further our understanding of how lipid signatures and lipid mediators are altered in disease and in health.
Rooms 4019, 4021
1510 Clifton Road, Atlanta, GA 30322
Rm 665B
Atlanta, GA 30322