Publications

  • Federici T, Riley J, Park J, Bain, M, Boulis N. (2009) Preclinical Safety Validation of a Stabilized Viral Vector Direct Injection Approach to the Cervical Spinal Cord. Clinical and Translational Science, 2(2): 165-7.
 
  • Riley J, Federici T, Park J, Suzuki M, Franz CK, Tork C, McHugh J, Teng Q, Svendsen C, Boulis NM. (2009) Cervical Spinal Cord Therapeutic Delivery: Preclinical Safety Validation of a Stabilized Microinjection Platform. Neurosurgery, 65(4):754-62.
 
  • Raore B, Federici T, Taub J, Wu MC, Riley J, Franz CK, Kliem MA, Snyder B, Feldman EL, Johe K, Boulis NM. (2011) Intraspinal Stem Cell Therapy: Assessment of Surgical Risks in Gottingen Minipigs. Spine, 36(3): E164-71.
 
  • Riley JP, Raore B, Taub JS, Federici T, Boulis NM. (2011) Platform and Cannula Design Improvements for Spinal Cord Therapeutics Delivery. Neurosurgery. Suppl2: 147-155.
 
  • Leung CH, Kliem MA, Heeke BL, McPhee SW, Federici T, Snyder BR, Boulis NM.  (2011) Assessment of Hippocampal Adeno-Associated Viral Vector Gene Delivery via Frameless Stereotaxis in a Nonhuman PrimateStereotactic Functional Neurosurgery, 89(5):275-85.
 
  • Federici T, Taub JS, Baum GR, Gray SJ, Grieger J, Matthews KA, Handy CR, Passini MA, Samulski RJ, Boulis NM. (2011) Robust Spinal Motor Neuron Transduction following Intrathecal Delivery of AAV9 in Pigs. Gene Therapy. Aug; 19(8):852-9.
 
  • Federici T, Hurtig CV, Burks KL, Riley JP, Krishna V, Miller BA, Sribnick EA, Miller JH, Grin N, Lamanna JJ, Boulis NM. (2012) Surgical Technique for Spinal Cord Delivery of Therapies Demonstration of Procedure in Gottingen Minipigs. JoVE. e4371.
 
  • Riley J, Glass J, Feldman EL, Polak M, Bordeau J, Federici T, Johe K, Boulis NM. (2014) Intraspinalstem cell transplantation in amyotrophic lateral sclerosis: a phase I trial, cervical microinjection, and final surgical safety outcomes. Neurosurgery. 74(1):77-87.
 
  • Passini MA, Bu J, Richards AR, Treleaven CM, Sullivan JA, O'Riordan CR, Scaria A, Kells AP, Samaranch L, San Sebastian W, Federici T, Fiandaca MS, Boulis NM, Bankiewicz K, Shihabuddin LS, Cheng SH. (2014) Translational Fidelity of Intrathecal Delivery of scAAV9-SMN1 for Spinal Muscular Atrophy. Human Gene Therapy. 25(7):619-30.
 
  • Gutierrez J, Lamanna JJ, Grin N, Hurtig CV, Miller JH, Riley J, Urquia L, Avalos P, Svendsen CN, Federici T, Boulis NM. (2015) Preclinical Validation of Multilevel Intraparenchymal Stem Cell Therapy in the Porcine Spinal Cord. Neurosurgery. 77(4):604-12.
 
  • Glass JD, Hertzberg VS, Boulis NM, Riley J, Federici T, Polak M, Bordeau J, Fournier C, Johe K, Hazel T, Cudkowicz M, Atassi N, Borges LF, Rutkove SB, Duell J, Patil PG, Goutman SA, Feldman EL. (2016) Transplantation of spinal cord-derived neural stem cells for ALS: Analysis of phase 1 and 2 trials. Neurology. 87(4):392-400.
 
  • Lamanna JJ, Urquia LN, Hurtig CV, Gutierrez J, Anderson C, Piferi P, Federici T, Oshinski JN, Boulis NM. (2017) Magnetic Resonance Imaging-Guided Transplantation of Neural Stem Cells into the Porcine Spinal Cord. Stereotact Funct Neurosurg. 95:60-68.
 
  • Lamanna JJ, Gutierrez J, Urquia LN, HurtigCV, Amador E, Grin N, Svendsen CN, Federici T, Oshinski JN, Boulis NM. (2017) Ferumoxytol labeling of human neural progenitor cells for diagnostic cellular tracking in the porcine spinal cord with magnetic resonance imaging. Stem Cells Translational Medicine. 6(1):139-150.
 
  • Lamanna JJ, Gutierrez J, Espinosa J, Wagner J, Urquia LN, Moreton C, Hurtig CV, Tora M, Kirk AD, Federici T, Boulis NM. (2017). Peripheral blood detection of systemic graft-specific xeno-antibodies following transplantation of human neural progenitor cells into the porcine spinal cord. Journal of Clinical Neuroscience. J Clin Neurosci. Oct 28. pii: S0967-5868(17)31053-6