Importing Animals
Animals may be shipped to and from external sources. The following details the methods of import and the options available to researchers seeking to import or export animals.
Options for Importing Animals into Emory
- Sperm rederivation via in vitro fertilization (IVF): yields heterozygotes delivered to your mouse room in about 2-3 months. Can add cryopreservation at additional cost to provide relief of housing live mice and enable disaster preparedness.
- Contact Emory Transgenic Mouse Facility (TMF) for details.
- Contact Emory Transgenic Mouse Facility (TMF) for details.
- Embryo rederivation: yields homozygotes or heterozygotes on background of choice. Can add cryopreservation at additional cost to provide relief of housing live mice and enable disaster resistance.
- Contact Emory Transgenic Mouse Facility (TMF) for details.
- Contact Emory Transgenic Mouse Facility (TMF) for details.
- Acute studies (aka "Quarantine Lite"): Investigators can import mice for acute studies. Breeding is permitted. Mice cannot be moved into the general population.
- Allows PI to conduct initial study to determine if line(s) is useful
- For short term and acute procedures
- Animals can be rederived using the Emory TMF for entry into general housing if desired.
- Mice are housed at ABSL2 per diem (see current rates) using ABSL2 practices
- Ivermectin (12 ppm) medicated feed is provided.
- Investigators are cautioned that while much is not known about the effects of ivermectin on research mice, there are known genotype-dependent risks of toxicity, immune modulation, behavioral alteration, and tissue-specific activation of CreT2. For more information about strain sensitivity, see the Ivermectin Fact Sheet.
- Exemptions from Ivermectin are considered on a case-by-case basis and are subject to PCR testing for consideration.
- Traditional Quarantine: Mice are imported and maintained in quarantine while being treated for fur mites and pinworms. Animal pathogen status is assessed upon arrival and prior to release. After the treatment and if results of health assessment are negative, these mice are released into the general population.
- Ivermectin (12 ppm) medicated feed is provided for 4 or more weeks.
- Investigators are cautioned that while much is not known about the effects of ivermectin on research mice, there are known genotype-dependent risks of toxicity, immune modulation, behavioral alteration, and tissue-specific activation of CreT2. For more information about strain sensitivity, see the Ivermectin Fact Sheet.
- For strains where toxicity is unknown, sufficient number of mice should be imported to allow for testing a small group (1 cage) for toxicity prior to treating entire group. This extends total quarantine time but should prevent the potential loss of the line.
Contact DAR Quarantine Services at DAR Transfers (Import/Export) with any questions or for information about all steps necessary for importation.